| Total Offense Attempts |
| Game |
| 1. | 69 | Steve Smith | vs. Notre Dame • 1989 |
| | | (68 passing, 1 rushing) | |
| Season |
| 1. | 512 | Steve Stenstrom | 1992 |
| | | (455 passing, 57 rushing) | |
| Career |
| 1. | 1,610 | Steve Stenstrom | 1991-94 |
| | | (1,380 passing, 230 rushing) | |
| | | | |
| Total Offense |
| Game |
| 1. | 447 | Todd Husak | vs. Oregon State • 1998 |
| 2. | 443 | Andrew Luck | at Arizona • 2009 |
| 3. | 438 | Steve Dils | at Washington State • 1978 |
| 4. | 428 | Todd Husak | at UCLA • 1998 |
| 5. | 418 | John Elway | at Ohio State • 1982 |
| | 418 | John Paye | at San Diego State • 1985 |
| 7. | 416 | Jim Plunkett | at Purdue • 1969 |
| 8. | 413 | John Paye | at Oregon • 1985 |
| | 413 | Steve Stenstrom | vs. Oregon State • 1993 |
| 10. | 410 | John Elway | at Purdue • 1981 |
| | | | |
| Season |
| 1. | 3,791 | Andrew Luck | 2010 |
| 2. | 3,667 | Andrew Luck | 2011 |
| 3. | 3,398 | Steve Stenstrom | 1993 |
| 4. | 3,203 | Kevin Hogan | 2015 |
| 5. | 3,189 | Jim Plunkett | 1970 |
| 6. | 3,104 | John Elway | 1982 |
| 7. | 3,087 | Kevin Hogan | 2014 |
| 8. | 3,033 | Steve Dils | 1978 |
| 9. | 3,026 | Todd Husak | 1998 |
| 10. | 2,985 | Kevin Hogan | 2013 |
| | | | |
| Career |
| 1. | 10,634 | Kevin Hogan | 2012-15 |
| 2. | 10,387 | Andrew Luck | 2009-11 |
| 3. | 10,179 | Steve Stenstrom | 1991-94 |
| 4. | 9,070 | John Elway | 1979-82 |
| 5. | 8,178 | Jim Plunkett | 1968-70 |
| 6. | 7,539 | John Paye | 1983-86 |
| 7. | 6,680 | Todd Husak | 1996-99 |
| 8. | 6,043 | Guy Benjamin | 1974-77 |
| 9. | 5,642 | Trent Edwards | 2003-06 |
| 10. | 4,701 | Jason Palumbis | 1988-91 |
